What is Cartrophen and how can it help my pet?

Cartrophen injections contain the active ingredient Pentosan Polysulfate which can be used in the treatment of osteoarthritis (OA), also known as degenerative joint disease (DJD). Cartrophen is given as a subcutaneous injection, usually at the back of the neck, as a weekly course for 4 weeks. Follow-up injections are given monthly initially, but the time-frame between injections will vary depending on your pet’s response.


Pentosan polysulfate is in a class of drugs known as Disease Modifying Osteoarthritis Drugs or DMOADs. It works on the sites of joint pain, providing pain relief, maintaining joint health and preserving joint cartilage.

Cartrophen helps improve the pain associated with degenerate joint disease by:

• Improving the quantity and quality of synovial (joint) fluid

• Stimulating cartilage production

• Inhibiting cartilage degrading enzymes, to stop the breakdown of cartilage

• Increasing blood supply and nutrition to the joint and subchondral bone (the layer of bone just under the cartilage in a joint)

And it has strong anti-inflammatory properties, which helps relieve the pain caused by inflammation.


In a word, YES. Pets that have been diagnosed with osteoarthritis sometimes have other diseases, so Cartrophen injections may be a safe choice of treatment.

Very rarely, your pet may be quieter than normal for 24-48 hours after a Cartrophen injection.

It has also been shown to have a temporary effect on blood coagulation (clotting). This side-effect is only short-lived, and has not yet been seen in our patients at the Albert Animal Hospital.

If you think your pet is suffering from osteoarthritis, please call us on 3208 9233 to book an appointment.

#furfamily #Veterinarian #Pain #PetHealth


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